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If such treatment is not tolerated or is contraindicated, a GLP-1 RA with proven cardiovascular outcomes benefit could be considered to reduce MACE and should be continued until kidney replacement therapy is indicated

The medication is most appropriate for adults with type 2 diabetes who require improved glycemic control, or for individuals with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

Why Combine LDN and Microdosing GLP-1

Some people in this situation also benefit from a slower titration schedule combined with the pyridoxine formulation

Indication expansion potential In addition to the traditional treatment of type 2 diabetes and obesity, this is also exploring potential uses for other metabolic diseases, such as non-alcoholic steatohepatitis, etc