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In the placebo group, typical total consumption over 30 days declined by 46%, much less but still a substantial amount, reflecting the placebo effect, the desire to reduce drinking, and the fact that participants received CBT therapy over the course of the trial

This timing recommendation is based on the medication's short-acting profile and its mechanism of slowing gastric emptying, which is most beneficial when timed with food intake

Otherwise, things are fairly similar between groups

North America GLP-1 Receptor Agonist Market: North America is registered to have largest market share in GLP-1 Receptor Agonist market in 2024