doi: 10.1038/s41598-022-11236-2 Summary Keywords metformin, rectal cancer, colorectal, radiosensitiser, energy metabolism, radioresistance Citation Buckley CE, OBrien RM, Nugent TS, Donlon NE, OConnell F, Reynolds JV, Hafeez A, ORordin DS, Hannon RA, Neary P, Kalbassi R, Mehigan BJ, McCormick PH, Dunne C, Kelly ME, Larkin JO, OSullivan J and Lynam-Lennon N (2023) Metformin is a metabolic modulator and radiosensitiser in rectal cancer
Glutathione is used by every cell as well as tissue in the body and prevents damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides
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The research includes anti-inflammatory mechanism considerations
Some users report transient fatigue during the first week after stopping, but whether this represents true peptide withdrawal or coincidental factors is unclear without controlled discontinuation studies.