Because tirzepatide already stimulates the GLP-1 pathway, adding semaglutide does not usually provide additional benefit
PREGNANCY, BREAST FEEDING AND FERTILITY PREGNANCY If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine
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For a drug to be approved for the pregnant population, it must go through rigorous testing with that population, and that has not yet happened for semaglutide or other GLP-1 (glucagon-like peptide 1) agonists, says Carrie Burns , MD, a board-certified endocrinologist and director of diabetes in pregnancy at Penn Medicine in Philadelphia
Molecules 26(23):7337 Trovato M (2020) A historical excursus of diagnostic methods for Hashimoto thyroiditis and Graves disease