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Additionally, inflammatory factors such as TNF-, IL-6, CRP, IL-12, IFN-, and NLRP3 inflammasome were elevated in various tissues, including those in the ovaries and follicular fluid (FF), adipose tissue, endometrium, intestine and liver ( Figure 2 )

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Semaglutide and Gut-Related Side Effects: What to Expect As effective as Semaglutide is, some individuals may experience temporary digestive side effects like nausea, bloating, or constipation