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129 In addition, the cholesterol homeostasis of cells is essential for the insulin secretion, as accumulated cholesterol in the plasma membrane resulting in impaired secretion via exocytosis, and reduced cholesterol in insulin granules making them enlarged, also resulting in secretory dysfunction

Each round of model optimisation was guided by cross-correlation between the map and the model

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We speculate that the resulting lack of energy coupled with the amplified destructive potential of elevated OxS (due to a lack of protective GSH) contributes to other aging hallmarks

The preservation of this neuronOLG unit not only guarantees the maintenance of saltatory conduction, but also provides the neurons with neuroprotective trophic support