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At our San Ramon practice, we use GHK-Cu to support treatment of fine lines and wrinkles, loss of firmness and elasticity, acne scars and other textural irregularities, hyperpigmentation, and overall skin dullness and thinning

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Interestingly, recent studies indicate that in the setting of ATII-induced hypertension, a downregulation of the dihydrofolate reductase was observed, which was accompanied by decreased vascular BH 4 levels and an uncoupled eNOS, 91 implicating a potential role of this salvage pathway in the development of hypertension