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Incretins effects on glucose homeostasis are mediated by several mechanisms, the most prominent being potentiation of insulin secretion

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In addition to the changes in energy metabolism during transition in dairy cows, various studies also confirmed endocrine, hematological and immunological changes ( A better understanding of temporal hematologic changes and of the impairment of leukocyte function around parturition may be important to enhance recovery, stabilize immunologic responses, and improve energy metabolism in cows

Conversely, blocking the Notch signal leads to the expression of Atoh1 , which induces secretory progenitors [20]