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Activation of fatty acids to highly polar thiol esters, i.e., acyl-CoA, occurs on the outer mitochondrial membrane, but to enable transport across the inner mitochondrial membrane, the acyl group is transferred to carnitine with formation of acylcarnitines, which can enter the mitochondria with the assistance of translocases

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A 2021 study found that taking a cranberry supplement for six months improved hepatic steatosis, or fatty liver, in people with NAFLD (Non Alcoholic Fatty Liver)