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Conditions such as multiple sclerosis (MS), autoimmune encephalitis, and pediatric neuropsychiatric syndromes like PANS and PANDAS are characterized by an immune system that mistakenly targets the brain, leading to symptoms ranging from brain fog and fatigue to seizures, cognitive decline, and severe behavioral changes

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In the brain, the PVN contains different neuronal populations related to appetite regulation, stress response, and other neuroendocrine functions [132,238], one of the neuronal populations linked to satiety signaling express GLP-1 receptors [132]

To view a copy of this licence, visit About this article Cite this article Li, T., Tian, Y., Zhong, Q