The condition is also associated with metabolic syndrome Metabolic syndrome Metabolic syndrome is a cluster of conditions that significantly increases the risk for several secondary diseases, notably cardiovascular disease, type 2 diabetes, and nonalcoholic fatty liver
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Further, GPx5, the cystine (active site) containing homotetrameric enzyme, is expressed exclusively in the epididymis to protect sperms from being damaged by hydrogen peroxide during their maturation [1, 8, 9]
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits
Interestingly, TSH and fT3 changes were completely reversible following significant weight loss (33% BMI decrease) [62]