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In contrast, Th17 cells are distinguished by the secretion of pro-inflammatory cytokines, such as IL-17 and IL-21, which are of great significance in initiating inflammatory responses and combating specific pathogens [144]
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After 26 weeks (6 months) of treatment at 7mg or 14mg doses
60,61 In the CNS, they play a major role in dynamic signaling such as clearing waste, tuning brain blood flow, regulating vascular function, ion hemostasis and balancing neuroimmune responses
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