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Researchers concerned about rebound effects after stopping GLP-1 therapies may find this mechanism particularly appealing

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Indications for GLP-1 agonist therapy include contraindications or intolerance to metformin or poorly controlled diabetes in patients already taking metformin

Patients taking compounded semaglutide also report rare but serious side effects of the drug, such as kidney problems, gallbladder disease, pancreatitis, changes in vision, hypoglycemia, and risk of thyroid c-cell tumors

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