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Average weight loss was ( 7.8 pounds (3.55 kg) for a 3.75/23 mg (phentermine/topiramate) dose 16 pounds (7.27 kg) for a 7.5/46 mg dose 18 pounds (8.25 kg) for a 15/92 mg dose In users of phentermine-topiramate, weight loss translated to a significant decrease in waist circumference as well as improved insulin sensitivity, improved blood sugar management, and reduction in blood pressure ( May be helpful for certain eating disorders The combination of phentermine and topiramate may help reduce binge eating in people with BED and bulimia nervosa

The core of this litigation targets major pharmaceutical companies, Novo Nordisk and Eli Lilly and Co., accusing them of failing to sufficiently warn users about the severe digestive side effects of GLP-1 class drugs, typically prescribed for diabetes management and weight loss

Body and head bends, reversals, duration of stillness periods, and movement duration until the first stop were measured

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