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After 2 months, most patients showed at least some improvement and at the 1-year follow-up, over 70% of patients still showed improvement

Common symptoms include: Persistent fatigue Low energy levels Shortness of breath Dizziness or feeling faint Irregular heartbeats (palpitations) Pale or yellowish skin Reduced appetite or unintentional weight loss If left untreated, B12 deficiency can lead to serious complications, including nerve damage, cognitive issues, and changes in mood

Percutaneous collagen induction therapy: Microneedling enhances topical active delivery

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Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice