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They are classified as ROS and reactive nitrogen species (RNS) (De Gara and Foyer, 2017)

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For instance, those with severe vitamin B12 deficiency may require weekly or biweekly shots until their blood levels return to normal

Common reasons include side effects (particularly nausea and vomiting), cost of ongoing private prescription, insufficient weight loss at tolerated doses, or switching to Mounjaro after learning about the SURMOUNT-5 trial results showing tirzepatides greater average efficacy

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