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This matters most for people who have trouble absorbing nutrients in the first place

When patients discontinue the medication, appetite-regulating hormones gradually normalize, and hunger signals return to baseline levels

Reyes JF, Ekmark-Lwen S, Perdiki M, Klingstedt T, Hoffmann A, Wiechec E, Nilsson P, Nilsson KPR, Alafuzoff I, Ingelsson M, Hallbeck M

The SURMOUNT-5 trial demonstrated that Zepbounds dual-agonist approach produces approximately 6% more weight loss compared to Wegovys GLP-1-only mechanism