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A reduced mitochondrial biogenesis through PGC-1/NRF1/TFAM (peroxisome proliferator-activated receptor- (PPAR- ) coactivator 1/nuclear respiratory factor-1/mitochondrial transcription factor A) was also observed [29]

29 Analyze Patent Thickets: Understand the evergreening strategiessuch as filing patents on new delivery devicesthat Big Pharma uses to delay competition

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