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Large amounts of sagging and/or loose skin usually mean that a tummy tuck or body lift will be needed, perhaps with liposuction or lipo contouring

Four of those trials were double-blinded and placebo-controlled: STEP 1 (N = 1,950, randomized 2:1, semaglutide to placebo), STEP 2 (N = 1,210, randomized 1:1:1 to semaglutide 1.0 mg, semaglutide 2.4 mg, or placebo weekly), STEP 3 (N = 611, randomized 2:1, semaglutide to placebo), and STEP 4 (N = 803, randomized 1:1, semaglutide to placebo)

[DOI] [PubMed] [Google Scholar] Panaro, B

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