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Furthermore, the activation of this signaling pathway by IGF-I can suppress -synuclein aggregation and toxicity, suggesting a possible therapeutically strategy in PD [130]

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To complete the transition to this new process, for codes for which we established interim final values in the CY 2016 PFS final rule with comment period (81 FR 80170), we reviewed the comments received during the 60-day public comment period following release of the CY 2016 PFS final rule with comment period (80 FR 70886), and re-proposed values for those codes in the CY 2017 PFS proposed rule