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Key aspects of energy modulation studies include: Brown adipose tissue (BAT) activation: Investigating SLU-PP-332's ability to stimulate BAT and increase energy expenditure Thermogenic gene expression: Examining the compound's effects on genes involved in thermogenesis and fat browning Metabolic rate: Measuring changes in basal metabolic rate and energy expenditure following SLU-PP-332 administration Body temperature regulation: Assessing the impact of SLU-PP-332 on core body temperature and heat production For energy modulation studies, researchers often employ a wider range of doses to capture both acute and chronic effects
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Journal of the American Geriatrics Society
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