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Semaglutide can affect menstrual patterns and tirzepatide can alter cycle timing , which may change the water retention pattern you were previously accustomed to

Baseline and follow-up laboratory monitoring (A1C, renal function, lipid panel) is advisable

Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP)

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While tirzepatide can improve cardiometabolic risk factors such as weight, blood pressure, and lipid profiles, the concurrent use of anabolic steroids may counteract these improvements and compound overall cardiovascular risk, particularly in individuals with pre-existing heart disease or multiple risk factors