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Studies from Sun et al

While studies and assessments of GLP-1 AOMs, such as the cost-effectiveness study by the Institute for Clinical and Economic Review (ICER), 24 emphasize the potential for improved outcomes in obesity-related chronic diseases (e.g., heart disease, diabetes, osteoarthritis) and the potential related savings, the cost of AOMs must be paid up front, often exceeding the political or financial capacity of state legislatures to fund the program adequately

The GHRH analog class in human RCTs (tesamorelin, the approved form) produced significant visceral adipose tissue reduction of ~10.9% at six months and ~18% at twelve months