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Following the whole-organ imaging, the brain was further sectioned via sagittal slices (2-3mm thickness) into two and then four pieces to better visualize the brain regions that semaglutide is known to interact with

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Although the fasting glucose levels in all ZDF rats subjected to different treatments were the same, liraglutide-treated rats showed a significant decrease the glucose level at each time point after oral glucose intake (Figure 1A, fourth panel)

Hickey WF, Hsu BL, Kimura H