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Variables associated with HbA1c and weight reductions when adding liraglutide to multiple daily insulin injections in persons with type 2 diabetes (MDI Liraglutide trial 3)

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Postmortem studies of PD brains have demonstrated microglial activation in the substantia nigra pars compacta (SNpc), characterized by increased expression of markers such as HLA-DR, CD68, and Iba-1, along with elevated production of pro-inflammatory mediators including IL-1, TNF-, IL-6, and reactive oxygen species (ROS) [73]