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Joint pain during tirzepatide treatment may result from rapid weight loss altering biomechanics and joint loading, increased physical activity unmasking pre-existing joint issues, or underlying conditions like osteoarthritis that are common in patients with obesity and type 2 diabetes

Mounjaro's Approved Uses in the UK In the United Kingdom, Mounjaro has received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) for two primary indications

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At the time, the drugmaker said it based the determination on the deceptive promotion and selling of illegitimate knockoff versions that put patient safety at risk.

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