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It's a naturally occurring copper-binding peptide first isolated from human plasma in 1973 by biochemist Loren Pickart, who noticed that older liver tissue regenerated better when exposed to plasma from younger donors

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Subsequent immunofluorescence staining revealed colocalization of FG signals with approximately 95% of DMV cells positive for choline acetyltransferase (ChAT), a marker of cholinergic neurons (Supplementary Fig