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The landmark Phase IIb clinical trial published in The Lancet (TIPO-1 study) evaluated 203 obese patients randomly assigned to receive tesofensine at doses of 0.25mg, 0.5mg, or 1.0mg daily for 24 weeks alongside an energy-restricted diet

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The Ozempic vs Wegovy article covers all the label and dosing differences between these two brand-name formulations of the same molecule

Lower DSIP levels have been correlated with depressive states, suggesting its involvement in hypothalamic-pituitary-adrenal (HPA) axis modulation ( 11 )

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