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It is also whether the symptom is mild, persistent, worsening, or linked with another health risk

10.1016/J.JBC.2024.107932 28 OkabeM

Quantitative changes in the mitochondrial proteome from subjects with mild cognitive impairment, early stage, and late stage Alzheimer's disease

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41 It is especially critical in pediatric care and for seniors over sixty-five, who use it at rates nearly 50 percent higher than younger Americans and depend on it for routine procedures such as hip replacements and cancer surgeries