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Certain types of Leukemia, a cancer of the blood or bone marrow 4

Perhaps better to focus on now and going forward rather than what's been before

NAD therapy may be particularly helpful for individuals whose NAD levels are depleted due to chronic stress, acute illness, or lifestyle factors

This makes the compound a cleaner tool for isolating fat-metabolism effects in experimental research where mitogenic side effects would confound results

NNMT inhibition as a therapeutic strategy has been explored in industry pharmaceutical pipelines (including a Pfizer program for non-alcoholic fatty liver disease that was reportedly discontinued in early clinical development), but no NNMT inhibitor has reached regulatory approval to date