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The cag PAI , a 40 kilobase segment of DNA is a group of about 30 genes, many of which encode components of type IV secretion system (T4SS) that acts as a "molecular syringe" through which cytotoxin-associated antigen (CagA), a protein encoded on the cag PAI, is translocated or "injected" into the epithelial cytosol causing powerful changes which is believed to benefit the bacterium

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