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These authors discussed the presence of circulating soluble DPP-4a DPP-4 form distinct from the enzymatic DPP-4and proposed that while enzymatic DPP-4 may be linked to obesity-associated inflammation and glucose regulation, soluble DPP-4 may have separate functions unrelated to inflammation [32]

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Off-label use may lead to unintended side effects or ineffective treatment, as the medication may not be suitable for the intended condition