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Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer

Others studies indicate that expression of phosphorylated Akt increases MDM2-mediated ubiquitination of p53 (Mayo and Donner, 2001)

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Its core vulnerability is chemical: the active sulfhydryl group (SH) on cysteine oxidises rapidly on exposure to gastric acid, digestive enzymes, heat, and light

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