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Methods: Following Cochrane guidelines for systematic reviews, we conducted an exhaustive search of electronic databases up to May 12, 2023, encompassing PubMed, Cochrane, Embase, Web of Science, Google Scholar, Natural Medicines, ProQuest, ClinicalTrials.gov, and ICTRP

An early study reported that gluconeogenic metabolic intermediates (PEP, pyruvic acid, and malic acid) can elevate intracellular ATP levels and are neuroprotective against MPP + in N2A cells

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These newer agents enable a more personalized balance between efficacy and safety through strategies such as add-back therapy to mitigate bone mineral density loss and vasomotor symptoms (7, 8)

Sermorelin and Its Role in Growth Hormone Therapy Sermorelin plays a unique role in growth hormone therapy