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Caerulein, a decapeptide cholecystokinin analogue, induces acute necrotizing pancreatitis in mice when given in high doses (50 micrograms/kg per h) over a period of 6 h

Phase 2 data demonstrated LDL cholesterol reductions of approximately 20%, a finding researchers have attributed to glucagon agonism-mediated effects on PCSK9 degradation

Am J Clin Nutr 1992;55:524S532S

Hindgut Hypothesis Another principle to explain the effect of BS on glucose homeostasis is the redirecting of food course via anatomical changes in gastrointestinal tract as seen with RYGB and BPD