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SOD protect cells against excessive O 2 levels by catalyzing the conversion of two O 2 into molecular oxygen and H 2 O 2 [44]

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Gene-specific hypermethylation of 25-hydroxylase, 1--hydroxylase, and VDR, and hypomethylation of CYP24A1 was observed in HFD-fed mice

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During a median follow-up of 27.5 months, lobar ICH events (OR 0.10, p = 0.015), presence of cSS (OR 0.19, p = 0.028), high white matter hyperintensities Fazekas score (OR 0.41, p = 0.007) were negatively associated with favorable outcome after adjustment for age, sex and immunosuppressive treatments

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