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Then, these 95 genes were entered into the STRING database to conduct a PPI network and 10 hub genes, including Akt1, Fn1, Trp53, Igf1, Itgb1, Jak2, Pik3r1, Nras, Hgf, and Myc, were found (Figure 5B)

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HeLa cells were treated with either ML226 or cell-permeable glutarate (diethylglutarate (DEG)), and lipoylation and glutaryl modifications were analyzed by immunoblot (Fig