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Published Research Oral BPC-157 in GI Models Sikiric et al
Taketa T, Correa AM, Sudo K, Blum MA, Wadhwa R, Skinner HD, Komaki R, Lee JH, Bhutani MS, Weston B, Liao ZX, Rice DC, Swisher SG , Hofstetter WL, Ajani AJ
Adding the second compound too early often leads to intense nausea and a forced step-down on one or both compounds
GLP-1 receptor activation slows gastric emptying (making food stay in the stomach longer, which extends satiety), reduces glucagon secretion (lowering blood sugar), and acts on hypothalamic neurons to reduce hunger drive
