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Elsevier, pp 729744 Checconi P, De Angelis M, Marcocci ME, Fraternale A, Magnani M, Palamara AT, Nencioni L (2020) Redox-modulating agents in the treatment of viral infections

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Fundamentally, aging is driven by the cumulative effects of cellular senescence ( The strategies to address senescent cells and replenish exhausted stem cells during the aging process, as well as supplementing metabolic substances like NAD+, gene therapy, or epigenetic approaches to mitigate aging, are different because they aim to promote the repair of senescent cells rather than inducing their apoptosis ( The Forkhead box O (FOXO) proteins are an important subclass of the Forkhead family