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Eligible studies recruited non-menopausal women with PCOS and evaluated GLP-1 receptor agonists, metformin, or myoinositol ( folic acid [FA]) alone or in combination versus placebo or active comparators

Am J Physiol Endocrinol Metab 283 : E1173E1177 Challis BG et al

Lower doses are typically used initially to assess tolerance and effectiveness

Con A-induced massive liver damage in WT mice but its damage was attenuated in Gpx1 KO mice