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Studies and real-world use suggest that the injectable formulation can offer a more predictable and manageable side effect profile for most patients
GLP-1 induced skin ageing is a new phenomenon that is affecting patients in different ways
Endogenous GLP-1 and GLP-1RAs differ significantly in their pharmacokinetics, mechanisms of action, and physiological effects
Gaps in GLP-1 treatment can cause withdrawal effects including appetite rebound, weight regain, and metabolic disruption
constipation, reflux, or intermittent nausea may continue Persistent or progressive symptoms rather than gradual improvement After month 3 Symptoms may remain mild or infrequent at a tolerated regimen New severe symptoms should not automatically be blamed on the medication The most important pattern is not simply "week 1 is bad and month 3 is good." A more accurate pattern is initiation, adaptation, possible symptom flare during dose escalation, and reassessment based on tolerability
