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Treatment is stage-dependent

While more research is needed before GLP-1s are used to manage neurodegenerative and cardiovascular disease, the pre-clinical studies look promising

10.1038/nm.2513 [DOI] [PMC free article] [PubMed] [Google Scholar] 113.Hansen AM, Bdvarsdottir TB, Nordestgaard DN, Heller RS, Gotfredsen CF, Maedler K, et al

When acetylcarnitine is injected directly into the brain, most of the acetyl groups were metabolized, as 60% of the injected acetylcarnitine was recovered as exhaled 14 CO 2 after 22 h, and the percentage recovered in the brain was 1.9, 1.6, 1.3, and 0.9% at 1, 3, 6, and 22 h, respectively [109]

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