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Scenario 2: Inadvertent Exposure 32-year-old woman with T2DM on semaglutide, presents at 8 weeks gestation G2P0L0A1.First trimester pregnancy loss due to high blood glucose levels Management- Stop Sema Reassurance based on current evidence Detailed risk counseling using available data HbA1C specially Enhanced monitoring with detailed ultrasound Multidisciplinary approach Documentation and registry participation if available What Guidelines Say

After years of use in practice, we use it in time-boxed, medically supervised courses (up to 12 months) with clear goals and monitoring

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Another population-based cohort study of patients with T2DM with a concomitant cancer showed that no increased risk of metastasis was associated with DPP-4 inhibitor therapy (Noh et al., 2019)