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The next most important role of carnitine is contributing to the catabolism of branched-chain ketoacids derived from branched-chain amino acids (valine, leucine, and isoleucine)

(B) Treatment was increased to 5 mg/kg doxorubicin equivalents twice weekly (saline: n = 14

The BBB thus protects the brain from toxic compounds present in the bloodstream, and inversely also filters harmful molecules from the brain which could reach the bloodstream

This study also indicates that when exogenous ALA is administered, a racemic mixture of ALA is often used [149]

These effects, observed in animal models, have been linked to improvements in muscle physiology and cardiac performance