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GLP-1 medications are designed to help regulate appetite, reduce cravings, and improve feelings of fullness

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Beyond deacetylation of histone proteins, HDACs also accept non-histone proteins as their substrates, finally affecting physiological and disease-related cellular processes, such as transcriptional machinery, DNA damage, signal transduction, protein folding, autophagy, and metabolism [60]

Clinical Evidence on Combined GLP-1 and Fasting Protocols Observational data from weight-loss programs combining GLP-1 therapy with time-restricted eating (a common IF variant) shows weight reduction of 15-22% over 24 weeks, compared to 8-12% with GLP-1 alone in comparable cohorts