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With GLP-1 pills , the medication sits in the stomach longer, which can lead to more upper-GI symptoms like reflux, stomach pain, and nauseaespecially since the pill must be taken on an empty stomach

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However, the massive use of GLP-1 agonists is under pharmacological surveillance, and evidence about long-term safety, efficacy and compliance is still being collected

(3) When patients with newly diagnosed diabetes are difficult to diagnose and cannot be clearly distinguished as having type 1 or type 2 diabetes, insulin therapy may be the preferred treatment