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Abstract The debilitating, chronic symptoms of neuropathic pain result in decreased quality of life, depressed mood, and anxiety in patients suffering from neuropathic pain

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[7] A real-life approach to consideration of MS might suggest that virtually any acute or chronic stressor that weakens the immune system toxic attack, intensified oxidative stress, illness from a garden variety virus or bacterium, malnutrition, even sustained emotional stress could conceivably create a time window for one of these organisms to enter the brain and establish itself