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CV risk factor improvements were seen at the mid-range doses of orforglipron, and higher doses did not result in further systematic reductions in these markers

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25, 38, 40 BSO+L-PAM was synergistic (CIN 0.30.7) in OPM-2 (t(4;14)(p16;q32)), NCI-H929 (t(4;14)) TX-MM-030h (post-BMT) and MOLP-2 (t(11;14)(q13;q32)) 39 cell lines (Figures 1ac)