Both drugs have reduced diabetes risk, improved blood glucose control, promoted weight loss, and decreased cardiovascular events compared with placebo in selected populations, although the populations, doses, and indications differed
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As these peptides are not FDA-approved and product quality varies, medical guidance, sterile technique, and attention to sourcing and legal considerations are essential to minimize risks
it showed that there was no evidence of a causal relationship between the FDA-approved GLP-1RAs and suicidality [109]
But four reached statistical significance, shown in the table below