doi:10.1080/00365521.1984.12005725.[Taylor & Francis Online], [Web of Science ] , [Google Scholar]) showed that the drug salazosulphapyrimidine (a constituent of sulphapyridine and 5-aminosalicylic acid) had a protective effect against PGN-induced lesions in Guinea pigs, though a slow release of 5-aminosalicylic acid alone did not
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Having a hot bath or sauna can help soothe tense muscles
Adding keto to this combination is generally manageable but may be unnecessary, given that three separate appetite-suppressing interventions could reduce intake to dangerously low levels
Persistent severe symptoms warrant clinical review, as 3.9% of participants discontinued therapy due to GI intolerance, especially if fluid loss led to dehydration